Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge typically rely on automated evaluations on limited benchmarks. There is no standard to evaluate model predictions and reasoning across a breadth of tasks. To address this, we present MultiMedQA, a benchmark combining six existing open question answering datasets spanning professional medical exams, research, and consumer queries; and HealthSearchQA, a new free-response dataset of medical questions searched online. We propose a framework for human evaluation of model answers along multiple axes including factuality, precision, possible harm, and bias. In addition, we evaluate PaLM (a 540-billion parameter LLM) and its instruction-tuned variant, Flan-PaLM, on MultiMedQA. Using a combination of prompting strategies, Flan-PaLM achieves state-of-the-art accuracy on every MultiMedQA multiple-choice dataset (MedQA, MedMCQA, PubMedQA, MMLU clinical topics), including 67.6% accuracy on MedQA (US Medical License Exam questions), surpassing prior state-of-the-art by over 17%. However, human evaluation reveals key gaps in Flan-PaLM responses. To resolve this we introduce instruction prompt tuning, a parameter-efficient approach for aligning LLMs to new domains using a few exemplars. The resulting model, Med-PaLM, performs encouragingly, but remains inferior to clinicians. We show that comprehension, recall of knowledge, and medical reasoning improve with model scale and instruction prompt tuning, suggesting the potential utility of LLMs in medicine. Our human evaluations reveal important limitations of today's models, reinforcing the importance of both evaluation frameworks and method development in creating safe, helpful LLM models for clinical applications.

深度学习方法为多级医学图像细分实现了令人印象深刻的表现。但是，它们的编码不同类别（例如遏制和排除）之间拓扑相互作用的能力受到限制。这些约束自然出现在生物医学图像中，对于提高分割质量至关重要。在本文中，我们介绍了一个新型的拓扑交互模块，将拓扑相互作用编码为深神经网络。该实施完全基于卷积，因此非常有效。这使我们有能力将约束结合到端到端培训中，并丰富神经网络的功能表示。该方法的功效在不同类型的相互作用上得到了验证。我们还证明了该方法在2D和3D设置以及跨越CT和超声之类的不同模式中的专有和公共挑战数据集上的普遍性。代码可在以下网址找到：https：//github.com/topoxlab/topointeraction

大型语言模型已被证明可以使用少量学习来实现各种自然语言任务的出色表现，这大大减少了将模型调整到特定应用程序所需的特定任务培训示例的数量。为了进一步了解量表对少量学习的影响，我们培训了一个5400亿个参数，密集激活的变压器语言模型，我们称之为“途径”语言模型棕榈。我们使用Pathways在6144 TPU V4芯片上训练了Palm，这是一种新的ML系统，可在多个TPU POD上进行高效的训练。我们通过在数百种语言理解和产生基准的基准方面实现最先进的学习结果来证明扩展的持续好处。在这些任务中，Palm 540B实现了突破性的表现，在一系列多步推理任务上表现出色，超过了最新的最新表现，并且在最近发布的Big Benchmark上表现优于平均人类表现。大量的大型基础任务显示出与模型量表的不连续改进，这意味着当我们扩展到最大模型时，性能急剧增加。 Palm在多语言任务和源代码生成方面也具有很强的功能，我们在各种基准测试中证明了这一点。我们还提供了有关偏见和毒性的全面分析，并研究了训练数据记忆的程度，相对于模型量表。最后，我们讨论与大语言模型有关的道德考虑，并讨论潜在的缓解策略。

Many recent works on understanding deep learning try to quantify how much individual data instances influence the optimization and generalization of a model, either by analyzing the behavior of the model during training or by measuring the performance gap of the model when the instance is removed from the dataset. Such approaches reveal characteristics and importance of individual instances, which may provide useful information in diagnosing and improving deep learning. However, most of the existing works on data valuation require actual training of a model, which often demands high-computational cost. In this paper, we provide a training-free data valuation score, called complexity-gap score, which is a data-centric score to quantify the influence of individual instances in generalization of two-layer overparameterized neural networks. The proposed score can quantify irregularity of the instances and measure how much each data instance contributes in the total movement of the network parameters during training. We theoretically analyze and empirically demonstrate the effectiveness of the complexity-gap score in finding 'irregular or mislabeled' data instances, and also provide applications of the score in analyzing datasets and diagnosing training dynamics.

In robotics and computer vision communities, extensive studies have been widely conducted regarding surveillance tasks, including human detection, tracking, and motion recognition with a camera. Additionally, deep learning algorithms are widely utilized in the aforementioned tasks as in other computer vision tasks. Existing public datasets are insufficient to develop learning-based methods that handle various surveillance for outdoor and extreme situations such as harsh weather and low illuminance conditions. Therefore, we introduce a new large-scale outdoor surveillance dataset named eXtremely large-scale Multi-modAl Sensor dataset (X-MAS) containing more than 500,000 image pairs and the first-person view data annotated by well-trained annotators. Moreover, a single pair contains multi-modal data (e.g. an IR image, an RGB image, a thermal image, a depth image, and a LiDAR scan). This is the first large-scale first-person view outdoor multi-modal dataset focusing on surveillance tasks to the best of our knowledge. We present an overview of the proposed dataset with statistics and present methods of exploiting our dataset with deep learning-based algorithms. The latest information on the dataset and our study are available at https://github.com/lge-robot-navi, and the dataset will be available for download through a server.

Crowdsourcing has emerged as an effective platform to label a large volume of data in a cost- and time-efficient manner. Most previous works have focused on designing an efficient algorithm to recover only the ground-truth labels of the data. In this paper, we consider multi-choice crowdsourced labeling with the goal of recovering not only the ground truth but also the most confusing answer and the confusion probability. The most confusing answer provides useful information about the task by revealing the most plausible answer other than the ground truth and how plausible it is. To theoretically analyze such scenarios, we propose a model where there are top-two plausible answers for each task, distinguished from the rest of choices. Task difficulty is quantified by the confusion probability between the top two, and worker reliability is quantified by the probability of giving an answer among the top two. Under this model, we propose a two-stage inference algorithm to infer the top-two answers as well as the confusion probability. We show that our algorithm achieves the minimax optimal convergence rate. We conduct both synthetic and real-data experiments and demonstrate that our algorithm outperforms other recent algorithms. We also show the applicability of our algorithms in inferring the difficulty of tasks and training neural networks with the soft labels composed of the top-two most plausible classes.

We address the problem of unsupervised domain adaptation when the source domain differs from the target domain because of a shift in the distribution of a latent subgroup. When this subgroup confounds all observed data, neither covariate shift nor label shift assumptions apply. We show that the optimal target predictor can be non-parametrically identified with the help of concept and proxy variables available only in the source domain, and unlabeled data from the target. The identification results are constructive, immediately suggesting an algorithm for estimating the optimal predictor in the target. For continuous observations, when this algorithm becomes impractical, we propose a latent variable model specific to the data generation process at hand. We show how the approach degrades as the size of the shift changes, and verify that it outperforms both covariate and label shift adjustment.

Scholarly text is often laden with jargon, or specialized language that divides disciplines. We extend past work that characterizes science at the level of word types, by using BERT-based word sense induction to find additional words that are widespread but overloaded with different uses across fields. We define scholarly jargon as discipline-specific word types and senses, and estimate its prevalence across hundreds of fields using interpretable, information-theoretic metrics. We demonstrate the utility of our approach for science of science and computational sociolinguistics by highlighting two key social implications. First, we measure audience design, and find that most fields reduce jargon when publishing in general-purpose journals, but some do so more than others. Second, though jargon has varying correlation with articles' citation rates within fields, it nearly always impedes interdisciplinary impact. Broadly, our measurements can inform ways in which language could be revised to serve as a bridge rather than a barrier in science.

The nonconvex formulation of matrix completion problem has received significant attention in recent years due to its affordable complexity compared to the convex formulation. Gradient descent (GD) is the simplest yet efficient baseline algorithm for solving nonconvex optimization problems. The success of GD has been witnessed in many different problems in both theory and practice when it is combined with random initialization. However, previous works on matrix completion require either careful initialization or regularizers to prove the convergence of GD. In this work, we study the rank-1 symmetric matrix completion and prove that GD converges to the ground truth when small random initialization is used. We show that in logarithmic amount of iterations, the trajectory enters the region where local convergence occurs. We provide an upper bound on the initialization size that is sufficient to guarantee the convergence and show that a larger initialization can be used as more samples are available. We observe that implicit regularization effect of GD plays a critical role in the analysis, and for the entire trajectory, it prevents each entry from becoming much larger than the others.

Hinged on the representation power of neural networks, neural radiance fields (NeRF) have recently emerged as one of the promising and widely applicable methods for 3D object and scene representation. However, NeRF faces challenges in practical applications, such as large-scale scenes and edge devices with a limited amount of memory, where data needs to be processed sequentially. Under such incremental learning scenarios, neural networks are known to suffer catastrophic forgetting: easily forgetting previously seen data after training with new data. We observe that previous incremental learning algorithms are limited by either low performance or memory scalability issues. As such, we develop a Memory-Efficient Incremental Learning algorithm for NeRF (MEIL-NeRF). MEIL-NeRF takes inspiration from NeRF itself in that a neural network can serve as a memory that provides the pixel RGB values, given rays as queries. Upon the motivation, our framework learns which rays to query NeRF to extract previous pixel values. The extracted pixel values are then used to train NeRF in a self-distillation manner to prevent catastrophic forgetting. As a result, MEIL-NeRF demonstrates constant memory consumption and competitive performance.